Symbicort alternatives — what works instead of budesonide/formoterol?

Need a different inhaler than Symbicort? Maybe your insurance changed, you’re getting side effects, or you want a cheaper option. Symbicort is a combined inhaled corticosteroid (ICS) and long-acting beta-agonist (LABA). The goal when swapping is to keep that anti-inflammatory plus long-acting bronchodilator effect. Below are real alternatives and practical tips to discuss with your doctor.

Common prescription alternatives

Dulera (mometasone/formoterol) — Very similar to Symbicort because it pairs an ICS with formoterol, a fast-acting LABA. Often a straightforward switch for adults.

Advair / AirDuo (fluticasone/salmeterol) — Uses salmeterol instead of formoterol. Works well for many people but has a slower onset than formoterol. Usually taken twice daily.

Breo Ellipta (fluticasone furoate/vilanterol) — Once-daily option for COPD and some adults with asthma. Convenient dosing can help adherence, but it may not fit every treatment plan.

Generic budesonide/formoterol — Generic versions of Symbicort are available in many places and can be much cheaper while providing the same active ingredients.

Trelegy (fluticasone/umeclidinium/vilanterol) — A triple therapy for COPD (adds a LAMA). Good if you need an extra bronchodilator, but usually overkill for asthma without COPD features.

LABA/LAMA combos (Anoro, Stiolto) — These are bronchodilator-only combos used primarily in COPD. They don’t contain an ICS, so they’re not a straight substitute if you need long-term inflammation control for asthma.

Practical tips when considering a switch

Ask about the active ingredients and dosing. One inhaler may use formoterol (fast on), another uses salmeterol (slower on). That affects how quickly you feel relief and how the inhaler fits your routine.

Check device type. MDIs (press-and-breathe) feel different from DPIs (breath-activated). If you use a spacer, moving to a DPI won’t work. Try a demo at the clinic or pharmacy.

Compare dosing frequency and strengths. Symbicort comes in specific budesonide/formoterol strengths. Your doctor should match steroid dose close to what you’re on now.

Think about cost and access. Generics and manufacturer coupons can cut costs. If you travel or need refills fast, ask about availability in your country.

Watch for side effects and control. After switching, track symptoms, rescue inhaler use, and side effects for 1–4 weeks and report changes to your clinician.

Final note: switching inhalers is common and safe when guided by a clinician. Bring up your symptoms, budget, and device preference—those details make the best alternative for you.

Lee Mckenna 4 January 2025

10 Effective Alternatives to Symbicort for Asthma and COPD Management

Discover the top 10 alternatives to Symbicort for managing asthma and COPD. This article provides detailed information on various inhalers and medications, such as Advair Diskus, Breo Ellipta, and Dulera, highlighting their effectiveness, pros, and cons. Understand the different options available to help you make informed decisions about your treatment plan.